Prostaglandin E1 Alcohol (Synonyms: 1hydroxy Prostaglandin E1, PGE1 Alcohol) |
カタログ番号GC18740 |
プロスタグランジンE1(PGE1)アルコールは、非刺激性の気管支拡張薬であり、0.01〜10.0 ug/mlの濃度でin vitroにおいて人間の気管支筋肉に対するPGE1と同等の弛緩作用を示します。
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Cas No.: 21562-57-2
Sample solution is provided at 25 µL, 10mM.
Prostaglandin E1 (PGE1) alcohol is a non-irritant bronchodilator, with relaxant activity on the human bronchial muscle in vitro, comparable to PGE1 at concentrations of 0.01 to 10.0 ug/ml. Asthmatics receiving single dose inhalation treatments reported significant but short-acting bronchodilation at doses of 10 and 30 ug. PGE1 alcohol binds to the mouse recombinant EP3 and EP4 receptors with Ki values of 330 and 190 nM, respectively.
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