NCGC00229600 |
| カタログ番号GC64079 |
NCGC00229600 は、甲状腺刺激ホルモン受容体 (TSHR) のアロステリック逆アゴニストです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1338824-20-6
Sample solution is provided at 25 µL, 10mM.
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NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves’ disease[1].
[1]. Neumann S, et al. A new small-molecule antagonist inhibits Graves’ disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.
Average Rating: 5 (Based on Reviews and 23 reference(s) in Google Scholar.)
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