NCGC00229600 |
Catalog No.GC64079 |
NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR).
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Cas No.: 1338824-20-6
Sample solution is provided at 25 µL, 10mM.
NCGC00229600 is an allosteric inverse agonist of thyrotropin receptor (TSHR). NCGC00229600 inhibits both TSH and stimulating antibody activation of TSHRs endogenously expressed in Graves’ disease[1].
[1]. Neumann S, et al. A new small-molecule antagonist inhibits Graves’ disease antibody activation of the TSH receptor. J Clin Endocrinol Metab. 2011 Feb;96(2):548-54.
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