Nicardipine (YC-93) |
| カタログ番号GC30986 |
ニカルジピン (YC-93) (YC-93 遊離塩基) は、心臓のカルシウム チャネルを遮断するための IC50 が 1 μM のカルシウム チャネル遮断薬です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 55985-32-5
Sample solution is provided at 25 µL, 10mM.
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Nicardipine(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage.
[1]. Huang BR, et al. Anti-neuroinflammatory effects of the calcium channel blocker nicardipine on microglial cells: implications for neuroprotection. PLoS One. 2014 Mar 12;9(3):e91167. [2]. Amenta F, et al. Vascular and neuronal hypertensive brain damage: protective effect of treatment with nicardipine. J Hypertens Suppl. 1996 Oct;14(3):S29-35. [3]. Gasior M, et al. Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice. J Neural Transm. 1996;103(7):819-31.
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