Pomalidomide-PEG1-azide |
| カタログ番号GC64769 |
ポマリドマイド-PEG1-アジドは、E3 リガーゼリガンド-リンカー複合体です。ポマリドマイド-PEG1-アジドには、ポマリドマイドベースのセレブロンリガンドとリンカーが組み込まれています。ポマリドマイド-PEG1-アジドを使用して、PROTAC BRD4 Degrader-1 を設計できます。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2133360-04-8
Sample solution is provided at 25 µL, 10mM.
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Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 [1].
[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.
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