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Pomalidomide-PEG1-azide

Katalog-Nr.GC64769

Pomalidomid-PEG1-Azid ist ein E3-Ligase-lgand-Linker-Konjugat. Pomalidomid-PEG1-Azid enthÄlt den auf Pomalidomid basierenden Cereblon-Liganden und einen Linker. Pomalidomid-PEG1-Azidkann verwendet werden, um einenPROTAC BRD4 Degrader-1 zu entwickeln.

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Pomalidomide-PEG1-azide Chemische Struktur

Cas No.: 2133360-04-8

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5 mg
281,00 $
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10 mg
450,00 $
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25 mg
844,00 $
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50 mg
1.350,00 $
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 [1].

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

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