[Pro3]-GIP (Rat) |
| カタログ番号GC50277 |
高親和性ラットGIP部分作動薬
Products are for research use only. Not for human use. We do not sell to patients.
![[Pro3]-GIP (Rat) 化学構造](/media/struct/GC5/GC50277.png "[Pro3]-GIP (Rat) 化学構造")
Sample solution is provided at 25 µL, 10mM.
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High affinity rat GIP receptor partial agonist (Kd = 13 nM). Increases cAMP accumulation in COS-7 cells transfected with rat GIP receptor, while also acting as a competitive antagonist of GIP.
Sparre-Ulrich et al (2016) Species-specific action of (Pro3)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptors. Br.J.Pharmacol. 173 27 PMID:26359804
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