Pyrantel tartrate |
カタログ番号GC32156 |
酒石酸ピランテルは、経口で活性な駆虫薬であり、ニコチン性アセチルコリン受容体 (nAChR) のアゴニストです。
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Cas No.: 33401-94-4
Sample solution is provided at 25 µL, 10mM.
Pyrantel tartrate is an antinematodal thiophene; nicotinic receptor agonist and can elicit spastic muscle paralysis in parasitic worms due to prolonged activation of the excitatory nicotinic acetylcholine (nACh) receptors on body wall muscle.
[1]. Aceves J, et al. The mechanism of the paralysing action of tetramisole on Ascaris somatic muscle. Br J Pharmacol. 1970 May;38(3):602-7. [2]. Aubry ML, et al. Aspects of the pharmacology of a new anthelmintic: pyrantel. Br J Pharmacol. 1970 Feb;38(2):332-44.
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