Ricinelaidic Acid |
カタログ番号GC41189 |
リシネライド酸は、12-ヒドロキシ脂肪酸であり、白血球トリエンB4(LTB4)受容体の拮抗剤です(豚好中球膜におけるKi = 2μM)。
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Cas No.: 540-12-5
Sample solution is provided at 25 µL, 10mM.
Ricinelaidic acid is a 12-hydroxy fatty acid and an antagonist of leukotriene B4 (LTB4) receptors (Ki = 2 µM in porcine neutrophil membranes). It inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50s = 10 and 7 µM, respectively). Ricinelaidic acid (1 mg/kg, i.v.) inhibits bronchoconstriction induced by LTB4 in rats by 46%.
Average Rating: 5
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