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Supercinnamaldehyde

カタログ番号GC18827

スーパーシナモアルデヒドは、一過性受容体ポテンシャルアンキリン1(TRPA1)チャネルの活性化剤であり(EC50 = 0.8 uM)、シナマルデヒドの類似体です。

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Supercinnamaldehyde 化学構造

Cas No.: 70351-51-8

サイズ 価格 在庫数 個数
1mg
$43.00
在庫あり
5mg
$134.00
在庫あり
10mg
$248.00
在庫あり
25mg
$378.00
在庫あり

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顧客レビュー

カスタマーレビューに基づきます。

Sample solution is provided at 25 µL, 10mM.

Description of Supercinnamaldehyde

Supercinnamaldehyde is an activator of the transient receptor potential ankyrin 1 (TRPA1) channel (EC50 = 0.8 uM) and an analog of cinnamaldehyde. TRPA1 is a nociceptor expressed on sensory neurons and is activated by hot and cold temperatures, mechanical stimuli, and pain.

Chemical Properties of Supercinnamaldehyde

Cas No. 70351-51-8 SDF
Chemical Name 1,3-dihydro-1-methyl-3-(2-oxopropylidene)-2H-indol-2-one
Canonical SMILES CN(C1=CC=CC=C1/C2=C/C(C)=O)C2=O
Formula C12H11NO2 M.Wt 201.2
溶解度 DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml,Ethanol: 2 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Supercinnamaldehyde

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.9702 mL 24.8509 mL 49.7018 mL
5 mM 994 μL 4.9702 mL 9.9404 mL
10 mM 497 μL 2.4851 mL 4.9702 mL
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計算

In vivo Formulation Calculator (Clear solution) of Supercinnamaldehyde

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 35 reference(s) in Google Scholar.)

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