TBK1 PROTAC® 3i |
| カタログ番号GC50745 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2052306-13-3
Sample solution is provided at 25 µL, 10mM.
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Potent TANK-binding kinase 1 (TBK1) Degrader (DC50 = 12 nM, Dmax = 96%). Exhibits >50-fold selectivity for TBK1 over the closely related IKKε. Comprises a ligand for von-Hippel Lindau (VHL) protein joined by a linker to a TBK1-targeting moiety. Brings about near complete degradation of TBK1 in mutant K-Ras and wild-type cancer cell lines with no significant effect of proliferation. Negative control TBK1 control PROTAC® 4 also available.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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