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TBK1 PROTAC® 3i

Catalog No.GC50745

Products are for research use only. Not for human use. We do not sell to patients.

TBK1 PROTAC® 3i Chemical Structure

Cas No.: 2052306-13-3

Size Price Stock Qty
5mg
$622.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Potent TANK-binding kinase 1 (TBK1) Degrader (DC50 = 12 nM, Dmax = 96%). Exhibits >50-fold selectivity for TBK1 over the closely related IKKε. Comprises a ligand for von-Hippel Lindau (VHL) protein joined by a linker to a TBK1-targeting moiety. Brings about near complete degradation of TBK1 in mutant K-Ras and wild-type cancer cell lines with no significant effect of proliferation. Negative control TBK1 control PROTAC® 4  also available.

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Average Rating: 5 ★★★★★ (Based on Reviews and 32 reference(s) in Google Scholar.)

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