tetranor-PGJM (Synonyms: tetranorPGJ Metabolite) |
カタログ番号GC18921 |
プロスタグランジンD2(PGD2)は、アレルギー性および喘息性アナフィラキシー、正常な生理的睡眠と体温低下に薬理学的役割を果たし、血小板凝集を抑制し、血管平滑筋を弛緩させます。
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Cas No.: 1352751-83-7
Sample solution is provided at 25 µL, 10mM.
Prostaglandin D2 (PGD2) plays a pharmacological role in allergic and asthmatic anaphylaxis, normal physiological sleep and lowering of body temperature, as well as inhibits platelet aggregation and relaxes vascular smooth muscle. tetranor-PGDM is an abundant urinary metabolite of PGD2 that is detectable both in human and mouse and, as such, is used as a biomarker of PGD2 biosynthesis. tetranor-PGJM is a potential PGD2 metabolite, formed by the elimination of the C-9 hydroxyl group. This compound may serve as a useful control in the analysis of PGD2 biosynthesis.
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