Thalidomide 4'-oxyacetamide-PEG3-amine |
| カタログ番号GC50462 |
サリドマイド 4'-オキシアセトアミド-PEG3-アミンは、PROTAC 技術で使用されるサリドマイド ベースのセレブロン リガンドと 3 ユニット PEG リンカーを組み込んだ合成 E3 リガーゼ リガンド-リンカー コンジュゲートです。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2245697-84-9
Sample solution is provided at 25 µL, 10mM.
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Functionalized cereblon ligand for PROTACsup>® research and development; incorporates an E3 ligase ligand plus a PEG linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. This product has been recently renamed. The previous name for this product was Thalidomide - linker 1 PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Winter et al (2015) Functionalized Cereblon ligand for PROTACs; incorporates an E3 ligase ligand and a linker used in PROTAC technology. Science 348 1376 PMID:25999370 |Salami et al (2017) Waste disposal-An attractive strategy for cancer therapy. Science 355 1163 PMID:28302825
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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