TP-472 |
| カタログ番号GC40628 |
TP-472 は選択的 BRD7/9 阻害剤であり、BRD7 と BRD9 の KD はそれぞれ 0.34 μM と 33 nM です。
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Cas No.: 2079895-62-6
Sample solution is provided at 25 µL, 10mM.
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TP-472 is an inhibitor of bromodomain BRD9 (Kd = 33 nM; EC50 = 320 nM in a NanoBRET assay). It has >30-fold selectivity over all other bromodomain family members with the exception of the highly homologous BRD7 bromodomain (Kd = 340 nM in an isothermal titration calorimetry (ITC) assay). See the Structural Genomic Consortium (SGC) website for more information.
Average Rating: 5 (Based on Reviews and 26 reference(s) in Google Scholar.)
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