Trapoxin A |
| カタログ番号GC18915 |
トラポキシンAは、サイクロテトラペプチドヒストンデアセチラーゼ（HDAC）阻害剤です。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 133155-89-2
Sample solution is provided at 25 µL, 10mM.
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Trapoxin A is a cyclotetrapeptide histone deacetylase (HDAC) inhibitor. It inhibits HDAC activity in a concentration-dependent and irreversible manner. Trapoxin A inhibits proliferation of NIH3T3 cells transformed by the oncogene v-sis (sis/NIH3T3; IC50 = ~200 ng/ml) and has detransformation activity, flattening sis/NIH3T3 cells when used at a concentration of 1 ng/ml. It also halts the cell cycle at the G2 phase in 3Y1 fibroblasts when used at a concentration of 10 nM and inhibits growth of TR303 cells resistant to trichostatin A at a concentration of 50 ng/ml.
Review for Trapoxin A
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
Review for Trapoxin A
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