2'-Deoxy-5'-O-DMT-2'-fluorouridine |
| Catalog No.GC67627 |
2'-Deoxy-5'-O-DMT-2'-뉴클레오사이드 유사체인 플루오로우리딘은 5'-O-DMTr-5-FUDR 유도체로서 강력한 항황열병(YFV) 활성을 가집니다.821d96072c2d58d8970e76f526b0f6b8
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 146954-74-7
Sample solution is provided at 25 µL, 10mM.
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2'-Deoxy-5'-O-DMT-2'-fluorouridine, a nucleoside analogue, is a 5'-O-DMTr-5-FUDR derivative with potent anti-yellow fever (YFV) activity[1].
2'-Deoxy-5'-O-DMT-2'-fluorouridine (compound 15h) has 100% inhibition against YFV at 20 mM. 2'-Deoxy-5'-O-DMT-2'-fluorouridine proves to be noncytotoxic at concen-trations up to 20 mM[1].
[1]. Christopher McGuigan, et al. Anti-flavivirus Activity of Different Tritylated Pyrimidine and Purine Nucleoside Analogues. ChemistryOpen. 2016 Jan 21;5(3):227-35.
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