>>Signaling Pathways>> PROTAC>> E3 Ligase Ligand-Linker Conjugate>>A 410099.1, amine

A 410099.1, amine

Catalog No.GC50466

A 410099.1, 아민은 기능이 없는 IAP 리간드이며 BTK를 표적으로 하는 PROTAC(PROTAC 4 및 5)와 같은 PROTAC의 합성에 사용할 수 있습니다.

Products are for research use only. Not for human use. We do not sell to patients.

A 410099.1, amine Chemical Structure

Cas No.: 2374122-37-7

Size 가격 재고 수량
100 mg
US$662.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized IAP ligand for PROTAC® research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Tinworth et al (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chem.Biol. 14 342 PMID:30807093

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