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A 410099.1, amine

カタログ番号GC50466

A 410099.1、アミンは機能化された IAP リガンドであり、BTK をターゲットとする PROTAC (PROTAC 4 および 5) などの PROTAC の合成に使用できます。

Products are for research use only. Not for human use. We do not sell to patients.

A 410099.1, amine 化学構造

Cas No.: 2374122-37-7

サイズ 価格 在庫数 個数
100 mg
$662.00
在庫あり

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Functionalized IAP ligand for PROTAC® research and development. Boc protected A 410099.1 (Cat.No. 6470). Supplied with an amine functional handle for ready conjugation to a linker/target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Tinworth et al (2019) PROTAC-mediated degradation of Bruton's tyrosine kinase is inhibited by covalent binding. ACS Chem.Biol. 14 342 PMID:30807093

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