AFMK (Synonyms: N-acetyl-N-formyl-5-Methoxykynuramine, NSC 688263) |
| Catalog No.GC41371 |
멜라토닌의 항산화 대사산물인 AFMK는 생쥐의 DNA, 단백질 및 지질에 대한 X선 유도 산화 손상을 약화시킵니다. AFMK는 더 가난한 청소부입니다. 생리학적 pH에서 AFMK의 pKa는 8.7입니다. 항산화 능력. AFMK는 세포 사멸 경로의 조절을 통해 PANC-1 세포에서 젬시타빈의 항종양 효과를 향상시킵니다.
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Cas No.: 52450-38-1
Sample solution is provided at 25 µL, 10mM.
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Melatonin is a neurotransmitter widely distributed in eukaryotes and is closely linked to circadean rhythms in mammals including humans. AFMK is a melatonin metabolite first identified in rat brain. AFMK has antioxidant and free radical scavenging activities in several experimental models. AFMK may also be measured in plasma as an index of melatonin synthesis and metabolism.
Average Rating: 5 (Based on Reviews and 21 reference(s) in Google Scholar.)
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