Amiprofos-methyl (Synonyms: APM, NSC 313446) |
| Catalog No.GC18274 |
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Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 36001-88-4
Sample solution is provided at 25 µL, 10mM.
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Amiprofos-methyl (APM) is a phosphoric amide herbicide. It reversibly decreases H. vulgare root and shoot length and inhibits in vitro polymerization of Rosa tubulin induced by paclitaxel in a dose-dependent manner. APM completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM. The antitubulin effects of APM are specific to plants as it has no effect on bovine brain tubulin polymerization at concentrations up to 100 μM. APM inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM. APM inhibits the growth of P. falciparum (IC50 = 3.5 μM) and completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM.
Review for Amiprofos-methyl
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
Review for Amiprofos-methyl
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