>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Potassium Channel>>AMP PNP

AMP PNP

Catalog No.GC50334

AMP PNP (아데닐릴-이미도디포스페이트 테트라리튬)은 ATP의 비가수 분석체로, KATP 채널을 억제합니다.

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AMP PNP Chemical Structure

Cas No.: 72957-42-7

Size 가격 재고 수량
1mg
US$54.00
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5mg
US$161.00
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10mg
US$284.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Non-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.

References:
[1].Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73 PMID:2412134 .
[2].Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484 PMID:4326768.
[3].Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231 PMID:7805625.

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