BAY 707 |
| Catalog No.GC50656 |
BAY 707은 IC50이 2.3nM인 MTH1(NUDT1)의 기질-경쟁적, 매우 강력하고 선택적인 억제제입니다. BAY 707은 다른 MTH1 화합물에 대해 우수한 약동학(PK) 프로필을 가지고 있으며 마우스에서 내약성이 우수하지만 시험관내 또는 생체내 항암 효능이 분명히 부족합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2109805-96-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective MTH1 inhibitor (IC50 = 2.3 nM). Exhibits no significant activity at 1 μM concentration against a panel of 97 kinases. Cell-permeable and active in vivo. Displays no antitumor activity in vitro or in vivo.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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