BAY 707 |
| Katalog-Nr.GC50656 |
BAY 707 ist ein substratkompetitiver, hochpotenter und selektiver Inhibitor von MTH1(NUDT1) mit einem IC50 von 2,3 nM. BAY 707 hat ein gutes pharmakokinetisches (PK) Profil im Vergleich zu anderen MTH1-Verbindungen und wird von Mäusen gut vertragen, zeigt jedoch einen deutlichen Mangel an In-vitro- oder In-vivo-Antikrebswirksamkeit.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2109805-96-9
Sample solution is provided at 25 µL, 10mM.
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Potent and selective MTH1 inhibitor (IC50 = 2.3 nM). Exhibits no significant activity at 1 μM concentration against a panel of 97 kinases. Cell-permeable and active in vivo. Displays no antitumor activity in vitro or in vivo.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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