HDAC-IN-4 (Synonyms: AZD 9468) |
| Catalog No.GC19190 |
HDAC-IN-4는 HDAC1, HDAC2 및 HDAC3에 대해 IC50이 각각 63nM, 570nM 및 550nM인 강력한 선택적 경구 활성 클래스 I HDAC 억제제입니다. HDAC-IN-4는 HDAC 클래스 II에 대한 활동이 없습니다. HDAC-IN-4는 항종양 활성이 있습니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 934828-12-3
Sample solution is provided at 25 µL, 10mM.
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CXD101 is a class I-selective HDAC inhibitor (HDAC1 (IC50, 63 nM), HDAC2 (IC50, 570 nM), HDAC3 (IC50, 550 nM). CXD101 has no activity against HDAC class II[1].
References:
[1]. Eyre TA, et al. Predictive biomarkers for disease sensitivity in lymphoma - the holy grail for HDAC inhibitors Oncotarget. 2018 Dec 18;9(99):37280-37281.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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