TAN 1364B (Synonyms: RK-682 (rac-1)) |
| Catalog No.GC41443 |
RK-682의 라세미체인 TAN 1364B는 단백질 티로신 포스파타제(PTPases) 억제제입니다. TAN 1364B는 단백질 티로신 포스파타제 1B(PTP-1B), 저분자량 단백질 티로신 포스파타제(LMW-PTP) 및 세포 분열 주기 25B(CDC-25B)를 억제하며 IC50은 8.6 μ, M8,878입니다. 각각 μM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 154639-24-4
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
TAN 1364B is a protein tyrosine phosphatase (PTP) inhibitor and the racemic and monomeric form of RK-682 . TAN 1364B inhibits the activity of the PTPs LMW-PTP, CDC25B, and PTP1B (IC50s = 8.6, 12.4, and 0.7 µM, respectively), but the inhibitory activity against LMW-PTP and CDC25B is blocked in the presence of magnesium. TAN 1364B forms aggregates in solution and binds to both the PTP binding site and to protein surfaces.
Average Rating: 5 (Based on Reviews and 28 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *