>>Signaling Pathways>> Immunology/Inflammation>> Reactive Nitrogen Species>>Ebselen Oxide

Ebselen Oxide (Synonyms: NSC 639772)

Catalog No.GC43584

Ebselen의 셀레논 유사체인 Ebselen oxide는 DGC(diguanylate cyclase)를 공유적으로 수정하여 c-di-GMP-수용체 상호작용을 억제하고 DGC 활성을 감소시킵니다.

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Ebselen Oxide Chemical Structure

Cas No.: 104473-83-8

Size 가격 재고 수량
1mg
US$64.00
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5mg
US$286.00
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10mg
US$508.00
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25mg
US$1,110.00
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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Ebselen is an excellent scavenger of peroxynitrite and is used for the treatment of cerebral infarctions. Ebselen oxide, formed by the oxidation of ebselen, lacks antioxidant activity, indicating that it can serve as a negative control for ebselen.[1]

Reference:
[1]. Lass, A., Witting, P., Stocker, R., et al. Inhibition of copper- and peroxyl radical-induced LDL lipid oxidation by ebselen: Antioxidant actions in addition to hydroperoxide-reducing activity. Biochimica et Biophysica Acta 1303, 111-118 (1996).

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