GSK 366 |
| Catalog No.GC36188 |
GSK 366은 인간 KMO 및 P에 대해 IC50이 2.3nM 및 0.7nM인 강력한 키누레닌-3-모노옥시게나제(KMO) 억제제입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1953157-39-5
Sample solution is provided at 25 µL, 10mM.
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GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor with IC50s of 2.3 nM and 0.7 nM for human KMO and P. fluorescens-KMO (Pf-KMO), respectively[1]. IC50: 2.3 nM (human KMO), 0.7 nM (Pf-KMO)[1]
[1]. Hutchinson JP, et al. Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun. 2017 Jun 12;8:15827.
Average Rating: 5 (Based on Reviews and 5 reference(s) in Google Scholar.)
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