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SPL-410

Katalog-Nr.GC37675

SPL-410 ist ein oral aktiver, hochpotenter und selektiver Hydroxyethylamin-basierter SPPL2a-Inhibitor (Signal Peptide Peptidase Like 2a) mit einem IC50 von 9 nM.

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SPL-410 Chemische Struktur

Cas No.: 2351886-00-3

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

SPL-410 is an orally active, highly potent and selective hydroxyethylamine based SPPL2a (Signal Peptide Peptidase Like 2a) inhibitor, with an IC50 of 9 nM[1]. IC50: 9 nM (SPPL2a)[1].

[1]. Velcicky J, et al. Discovery of Orally Active Hydroxyethylamine Based SPPL2a Inhibitors. ACS Med Chem Lett. 2019 May 23;10(6):887-892.

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