N-Methylisatoic anhydride |
| Katalog-Nr.GC38314 |
N-MethylisatosÄureanhydrid (NMIA) ist ein 2'-OH-selektives Acylierungsmittel von RNAs und wird hÄufig zur AuflÖsung sekundÄrer RNA-Strukturen unter Verwendung der SHAPE-Technologie (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) verwendet.
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Cas No.: 10328-92-4
Sample solution is provided at 25 µL, 10mM.
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N-Methylisatoic anhydride (NMIA) is a 2'-OH selective acylation agent of RNAs, and is widely used forresolving secondary RNA structures using the SHAPE (Selective 2'-Hydroxyl Acylation Analyzed by Primer Extension) technology[1].
[1]. Ursuegui S, et al. Biotin-conjugated N-methylisatoic anhydride: a chemical tool for nucleic acid separation by selective 2'-hydroxyl acylation of RNA. Chem Commun (Camb). 2014 Jun 1;50(43):5748-51.
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