Glabrol |
| Catalog No.GC38636 |
감초 뿌리의 에탄올 추출물에서 분리된 하나의 이소프레닐 플라보노이드인 Glabrol(화합물 1)은 쥐 간 마이크로솜 ACAT 활성에 대해 IC50 값이 24.6μM인 강력하고 비경쟁적인 Acyl-coenzyme A: 콜레스테롤 아실트랜스퍼라제(ACAT) 억제제입니다[ 1].
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 59870-65-4
Sample solution is provided at 25 µL, 10mM.
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Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].
Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1].
[1]. Choi JH, et al. Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. J Ethnopharmacol. 2007 Apr 4;110(3):563-6.
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