Glabrol |
| Katalog-Nr.GC38636 |
Glabrol (Verbindung 1), ein Isoprenylflavonoid, das aus Ethanolextrakt von SÜßholzwurzeln isoliert wurde, ist ein potenter und nicht kompetitiver Acyl-Coenzym A: Cholesterin-Acyltransferase (ACAT)-Inhibitor mit einem IC50-Wert von 24,6 μM fÜr die mikrosomale ACAT-AktivitÄt von Rattenleber[ 1].
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Cas No.: 59870-65-4
Sample solution is provided at 25 µL, 10mM.
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Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].
Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1].
[1]. Choi JH, et al. Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. J Ethnopharmacol. 2007 Apr 4;110(3):563-6.
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