Glabrol |
カタログ番号GC38636 |
Glabrol (化合物 1)、1 つのイソプレニル フラボノイドは、甘草の根のエタノール抽出物から分離され、強力で非競合的なアシル補酵素 A: コレステロール アシルトランスフェラーゼ (ACAT) 阻害剤であり、ラット肝臓ミクロソーム ACAT 活性に対して 24.6 μM の IC50 値を有する[ 1]。
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Cas No.: 59870-65-4
Sample solution is provided at 25 µL, 10mM.
Glabrol (Compound 1), One isoprenyl flavonoid was isolated from ethanol extract of licorice roots, is a potent and non-competitive Acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor with an IC50 value of 24.6 μM for rat liver microsomal ACAT activity[1].
Glabrol (Compound 1) decreases cholesteryl ester formation with an IC50 value of 26.0 μM in HepG2 cells[1].
[1]. Choi JH, et al. Glabrol, an acyl-coenzyme A: cholesterol acyltransferase inhibitor from licorice roots. J Ethnopharmacol. 2007 Apr 4;110(3):563-6.
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