L-Moses (hydrochloride) (Synonyms: L-45) |
Catalog No.GC45503 |
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
L-Moses is an inhibitor of the p300/CBP-associated factor (PCAF) bromodomain (Kd = 126 nM).1 It is selective for PCAF over GCN5 (Kd = 600 nM) and >4,500-fold selective for PCAF over BRD4. L-Moses displaces the PCAF bromodomain from histone H3.3 in a nanoBRET target engagement assay when used at a concentration of 5 μM.
References
1. Moustakim, M., Clark, P.G.K., Trulli, L., et al. Discovery of a PCAF Bromodomain Chemical Probe. Angew Chem. Int. Ed. Engl. 56(3), 827-831 (2017).
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