>>Signaling Pathways>> Microbiology & Virology>> SARS-CoV>>GRL0617

GRL0617

Catalog No.GC39172

SARS-CoV와 SARS-CoV-2 PLpro 억제제

Products are for research use only. Not for human use. We do not sell to patients.

GRL0617 Chemical Structure

Cas No.: 1093070-16-6

Size 가격 재고 수량
10mM (in 1mL DMSO)
US$270.00
재고 있음
5mg
US$245.00
재고 있음
10mg
US$455.00
재고 있음

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고객 리뷰

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro)/deubiquitinase, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM[1].

[1]. Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.

리뷰

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Average Rating: 5 ★★★★★ (Based on Reviews and 25 reference(s) in Google Scholar.)

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