GRL0617 |
| Katalog-Nr.GC39172 |
Ein SARS-CoV und SARS-CoV-2 PLpro-Inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1093070-16-6
Sample solution is provided at 25 µL, 10mM.
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GRL0617 is a potent, selective and competitive noncovalent inhibitor of severe acute respiratory syndrome (SARS-CoV) papain-like protease (PLpro)/deubiquitinase, with an IC50 of 0.6 μM, and with a Ki of 0.49 μM[1].
[1]. Ratia K, et al. A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication. Proc Natl Acad Sci U S A. 2008 Oct 21;105(42):16119-24.
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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