Hexapeptide-11 (acetate) (Synonyms: FVAPFP, Phe-Val-Ala-Pro-Phe-Pro) |
| Catalog No.GC45639 |
A synthetic hexapeptide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: N/A
Sample solution is provided at 25 µL, 10mM.
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Hexapeptide-11 is a synthetic hexapeptide.1 Hexapeptide-11 (5% v/v) increases the expression of the antioxidant genes Nrf2, Keap1, NQO1, and TXNRD1 and decreases hydrogen peroxide-induced senescence of IMR-90 human lung fibroblasts in vitro. Hexapeptide-11 (5% v/v) increases the activity of matrix metalloproteinase-2 (MMP-2) and MMP-9 and the proteasome peptidases LLVY/β5 and LLE/β1 in IMR-90 cells in vitro and reduces the migration of IMR-90 cells in a scratch wound assay.
|1. Sklirou, A.D., Ralli, M., Dominguez, M., et al. Hexapeptide-11 is a novel modulator of the proteostasis network in human diploid fibroblasts. Redox Biol. 5, 205-215 (2015).
Average Rating: 5 (Based on Reviews and 33 reference(s) in Google Scholar.)
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