L-Glutathione Reduced (Synonyms: GSH) |
Catalog No.GC12203
One-Click Copy Product Info
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Cas No.: 70-18-8
Sample solution is provided at 25 µL, 10mM.
L-Glutathione Reduced(GSH; γ-L-글루탐일-L-시스테인일-글리신)은 내원성 항산화제이고 산소 유래 자유 라디칼을 제거할 수 있다.
L-Glutathione Reduced은 생체 세포에 널리 존재하는 비단백질 티올이고 생물체 내에서 단백질과 DNA 합성, 효소 활성, 대사 및 세포 보호 등 중요한 생물학적 기능을 한다. L-Glutathione Reduced은 산소 유래 활성산소를 제거할 수 있고 산화 스트레스의 지표로 설정되었다 [1].
References:
[1]. Pereira-Rodrigues N, et al. Electrocatalytic activity of cobalt phthalocyanine CoPc adsorbed on a graphite electrode for the oxidation of reduced L-glutathione (GSH) and the reduction of its disulfide (GSSG) at physiological pH. Bioelectrochemistry. 2007 Jan;70(1):147-54.
| Cas No. | 70-18-8 | SDF | |
| Synonyms | GSH | ||
| Chemical Name | (S)-2-amino-5-(((R)-1-((carboxymethyl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-5-oxopentanoic acid | ||
| Canonical SMILES | SC[C@@H](C(NCC(O)=O)=O)NC(CC[C@@H](C(O)=O)N)=O | ||
| Formula | C10H17N3O6S | M.Wt | 307.32 |
| Solubility | ≥ 14.25mg/mL in Water | Storage | 4°C, protect from light, stored under nitrogen,unstable in solution, ready to use. |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
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1 mg | 5 mg | 10 mg |
| 1 mM | 3.2539 mL | 16.2697 mL | 32.5394 mL |
| 5 mM | 650.8 μL | 3.2539 mL | 6.5079 mL |
| 10 mM | 325.4 μL | 1.627 mL | 3.2539 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >97.00% Appearance: A solid
- COA (Certificate of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)