N-Acetyl-L-leucyl-L-leucyl-L-methional |
Catalog No.GC50002 |
Cathepsin inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 145757-50-2
Sample solution is provided at 25 µL, 10mM.
Very potent inhibitor of cathepsin L (Ki = 0.6 nM) and the strongest inhibitor of cathepsin B (Ki = 100 nM) amongst the peptide aldehydes. Also inhibits processing of malaria aspartic hemoglobinases plasmepsins I and II in vitro.
Francis et al (1997) Biosynthesis and maturation of the malaria aspartic hemogloninases plasmepsins I and II. J.Biol.Chem. 272 14961 PMID:9169469 |Sasaki et al (1990) Inhibitory effect of di- and tripeptidyl aldehydes on calpains and cathepsins. J.Enzyme Inhib. 3 195 PMID:2079636
Average Rating: 5
(Based on Reviews and 18 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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