Nelfinavir |
| Catalog No.GC17709 |
Nelfinavir(AG-1341)는 HIV 감염에 대한 강력하고 경구 생체이용 가능한 HIV-1 프로테아제 억제제(Ki=2nM)입니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 159989-64-7
Sample solution is provided at 25 µL, 10mM.
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Nelfinavir (AG-1341) is a potent and orally bioavailable HIV-1 protease inhibitor (Ki=2 nM) and antiviral agent for the treatment of HIV infection. Nelfinavir is a broad-spectrum, anticancer agent[1][2][3].
References:
[1]. Mondal D, et al. Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones. Ochsner J. 2013 Spring;13(1):76-90.
[2]. Gills JJ, et al. Nelfinavir, A lead HIV protease inhibitor, is a broad-spectrum, anticancer agent that inducesendoplasmic reticulum stress, autophagy, and apoptosis in vitro and in vivo. Clin Cancer Res. 2007 Sep 1;13(17):5183-94.
[3]. Kaldor SW, et al. Viracept (nelfinavir mesylate, AG1343): a potent, orally bioavailable inhibitor of HIV-1 protease. J Med Chem. 1997 Nov 21;40(24):3979-85.
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
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