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홈 >> Signaling Pathways >> Metabolism >> Bone Growth & Remodeling

Bone Growth & Remodeling

Products for  Bone Growth & Remodeling

  1. Cat.No. 상품명 정보
  2. GC49890 β-Glycerophosphate-d5 (sodium salt hydrate)

    Glycerol 2-Phosphate-d5

     An internal standard for the quantification of β-glycerophosphate β-Glycerophosphate-d5 (sodium salt hydrate) Chemical Structure
  3. GC41410 11β-Prostaglandin E2

    11β-PGE2

     11β-프로스타글란딘 E2(11β-디노프로스톤), 프로스타노이드 유도체는 53.3nM의 Ki로 쥐의 시상하부 막에 대한 [3H]PGE2 결합을 억제합니다. 11β-Prostaglandin E2 Chemical Structure
  4. GC91109 17β-Estradiol 3-O-Sulfate (sodium salt)

    17β-에스트라디올의 비활성 대사산물

     17β-Estradiol 3-O-Sulfate (sodium salt) Chemical Structure
  5. GC90945 17β-Estradiol-2,4,16,16-d4 3-sulfate (sodium salt)

    17β-에스트라디올-3-설페이트의 양적 분석을 위한 내부 표준입니다.

     17β-Estradiol-2,4,16,16-d4 3-sulfate (sodium salt) Chemical Structure
  6. GC41300 17β-hydroxy Exemestane 17β-hydroxy Exemestane is the primary active metabolite of exemestane. 17β-hydroxy Exemestane Chemical Structure
  7. GC46471 17β-hydroxy Exemestane-d3 A neuropeptide with diverse biological activities 17β-hydroxy Exemestane-d3 Chemical Structure
  8. GC52129 3-Amino-5-hydroxybenzoic Acid

    AHBA

     3-Amino-5-hydroxybenzoic Acid Chemical Structure
  9. GC46080 7,3',4'-Trihydroxyflavone

    3’,4’,7-Trihydroxyflavone, 5-Deoxyluteolin

     7,3',4'-Trihydroxyflavone은 넓은 콩 꼬투리에서 분리된 플라보노이드 아글리콘 화합물입니다. 7,3',4'-Trihydroxyflavone Chemical Structure
  10. GC46768 Abaloparatide (acetate)

    BA 058, BIM 44058

     A synthetic derivative of PTHrP and an agonist of PTHR1 Abaloparatide (acetate) Chemical Structure
  11. GC42715 Ac-VDVAD-CHO (trifluoroacetate salt)

    Ac-Val-Asp-Val-Ala-Asp-CHO

     Ac-VDVAD-CHO is an inhibitor of caspase-2, -3, and -7 (Kis = 3.5, 1, and 7.5 nM, respectively). Ac-VDVAD-CHO (trifluoroacetate salt) Chemical Structure
  12. GC42691 Aceclofenac ethyl ester A potential impurity found in commercial preparations of aceclofenac Aceclofenac ethyl ester Chemical Structure
  13. GC42692 Aceclofenac methyl ester

    Aceclofenac Impurity D

     A potential impurity in commercial preparations of aceclofenac Aceclofenac methyl ester Chemical Structure
  14. GC90949 Adenosine-5'-O-(3-thiotriphosphate) (sodium salt)

    P2Y11 수용체 작용제

     Adenosine-5'-O-(3-thiotriphosphate) (sodium salt) Chemical Structure
  15. GC41541 Alizarin-3-methyliminodiacetic Acid

    Alizarin Complexone, Alizarin Fluorine Blue, NSC 293056

     Alizarin-3-methyliminodiacetic Acid는 칼슘 추적자이자 킬레이트제입니다. Alizarin-3-methyliminodiacetic Acid Chemical Structure
  16. GC42815 Ansatrienin A

    Mycotrienin I

     Ansatrienin A is an ansamycin antibiotic and antifungal agent first isolated from S. Ansatrienin A Chemical Structure
  17. GC19508 BLU-782

    Activin Receptor-like Kinase 2 Inhibitor 1, ALK2-IN-1, Fidrisertib

    BLU-782는 경구 활성을 가진 액티비닌 수용체 유사 활성효소 2 (ALK2) 억제제로 ALK2R206H, ALK2, ALK1, ALK6, ALK3, ALK4 및 ALK5에 대한 IC50 값은 각각 0.2nM, 0.6nM, 3nM, 24nM, 45nM, 65nM 및 155nM이다.

     BLU-782 Chemical Structure
  18. GC52376 BMP2-derived Peptide (trifluoroacetate salt)

    Bone Morphogenic Protein 2-derived Peptide, KIPKASSVPTELSAISTLYL-NH2

     A synthetic peptide BMP2-derived Peptide (trifluoroacetate salt) Chemical Structure
  19. GC43126 Calcitonin (human) (trifluoroacetate salt)

    Ba 47175, Calcitonin (1-32) (human), hCT, Thyrocalcitonin (human)

     Calcitonin is a peptide hormone that lowers blood calcium levels and inhibits bone resorption. Calcitonin (human) (trifluoroacetate salt) Chemical Structure
  20. GC43127 Calcitonin (salmon) (trifluoroacetate salt)

    Calcitonin (1-32) (salmon), Salcatonin, sCT, Thyrocalcitonin (salmon)

     Calcitonin is a peptide hormone that lowers blood calcium level and inhibits bone resorption. Calcitonin (salmon) (trifluoroacetate salt) Chemical Structure
  21. GC18498 Cathepsin L Inhibitor (Z-FY-CHO)

    SB 412515; Z-FY-CHO

     Cathepsin L Inhibitor (Z-FY-CHO)는 Cathepsin L의 활성을 특이적으로 억제할 수 있는 (Ki = 0.185nM) 화합물이고 세포 내에서 Cathepsin L이 소체 기능과 단백질 분해에 미치는 역할을 연구하기 위해 사용된다. Cathepsin L Inhibitor (Z-FY-CHO) Chemical Structure
  22. GC47090 Cinacalcet-d3 (hydrochloride)

    AMG 073-d3

     A neuropeptide with diverse biological activities Cinacalcet-d3 (hydrochloride) Chemical Structure
  23. GC43307 Concanamycin B

    8deethyl8methylConcanamycin A, MCH 210

     Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+-ATPases, also known as V-ATPases (IC50 = 5 nM). Concanamycin B Chemical Structure
  24. GC39623 DCC-3014

    DCC-3014

     DCC-3014(DCC-3014)는 특허 WO2014145025A2, 화합물 실시예 10에서 추출한 c-FMS(CSF-IR) 및 c-Kit 이중 억제제이며, IC50s는 각각 <0.01 μM 및 0.787879887입니다. . DCC-3014 Chemical Structure
  25. GC43567 DPC-AJ1951 (trifluoroacetate salt) DPC-AJ1951 is a peptide agonist of the parathyroid hormone (PTH)/PTH-related peptide receptor (PPR; EC50 = 0.15 nM in HEK293 cells expressing human PPR). DPC-AJ1951 (trifluoroacetate salt) Chemical Structure
  26. GC47287 Eltenac 비스테로이드성 소염진통제(NSAID)인 엘테낙은 COX 억제제이다. Eltenac Chemical Structure
  27. GC18230 ethyl 2,5-Dihydroxybenzoate

    ethyl Gentisate

     ethyl 2,5-Dihydroxybenzoate is a dual modulator of bone cell differentiation. ethyl 2,5-Dihydroxybenzoate Chemical Structure
  28. GC49303 Ganoderic Acid DM Ganoderma lucidum에서 분리된 천연 트리테르페노이드인 Ganoderic acid DM은 인간 유방암 세포에서 DNA 손상, G1 세포 주기 정지 및 세포자멸사를 유도합니다. Ganoderic Acid DM Chemical Structure
  29. GC49416 Gap 27 (trifluoroacetate salt)

    43Gap27, SRPTEKTIFII

     A connexin-mimetic peptide Gap 27 (trifluoroacetate salt) Chemical Structure
  30. GC91768 GSK205 (hydrobromide) GSK205 is an inhibitor of transient receptor potential vanilloid 4 (TRPV4) and transient receptor potential ankyrin 1 (TRPA1; IC50s = 4.19 and 5.56 µM, respectively, for the rat channels). GSK205 (hydrobromide) Chemical Structure
  31. GC47417 GW 9662-d5 A neuropeptide with diverse biological activities GW 9662-d5 Chemical Structure
  32. GC49305 H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt)

    H-RGDC-OH

     An RGD-containing tetrapeptide H-Arg-Gly-Asp-Cys-OH (trifluoroacetate salt) Chemical Structure
  33. GC91449 Ipamorelin (acetate)

    Aib-His-D-2-Nal-D-Phe-Lys-NH2; NNC 26-0161

    이파모렐린은 5개의 아미노산으로 이루어진 성장 호르몬 분비 유도제(GHS) 및 GHS 수용체 1a (GHS-R1a) 작용제입니다.

     Ipamorelin (acetate) Chemical Structure
  34. GC44010 KMN-80 PGE1의 유도체인 KMN-80은 IC50과 Ki가 각각 3nM 및 2.35nM인 EP4 수용체의 선택적이고 강력한 작용제입니다. KMN-80 Chemical Structure
  35. GC60970 KY19382

    A3051

     KY19382는 각각 IC50이 19 및 10nM인 CXXC5-DVL 및 GSK3β의 강력한 경구 활성 이중 억제제입니다. KY19382 Chemical Structure
  36. GC47538 L-Ascorbic Acid 2-phosphate (magnesium salt hydrate)

    AA2P, Ascorbyl PM, L-Ascorbic Acid 2-phosphate (magnesium salt), Phospitan C

     L-Ascorbic Acid 2-phosphate (magnesium salt hydrate)은 세포 및 조직 치료의 원료로 주로 사용되는 비타민 C 유도체이다. L-Ascorbic Acid 2-phosphate (magnesium salt hydrate) Chemical Structure
  37. GC47619 Menaquinone 4-d7

    MK-4-d7, Vitamin K2(20)-d7

     메나퀴논 4-d7(비타민 K2(MK-4)-d7)은 메나퀴논-4로 표시된 중수소입니다. Menaquinone-4는 비타민 K로 지혈제로 사용되며 골다공증의 통증에 대한 보조 요법으로도 사용됩니다. Menaquinone 4-d7 Chemical Structure
  38. GC46175 MOTS-c (human) (trifluoroacetate salt)

    Mitochondrial open reading frame of the 12S rRNA-c

     A neuropeptide with diverse biological activities MOTS-c (human) (trifluoroacetate salt) Chemical Structure
  39. GC44445 N-Oleoyl-L-Serine Bone mass and shape is continuously remodeled by the concerted and balanced action of osteoblasts (bone forming cells) and osteoclasts (bone-resorbing cells). N-Oleoyl-L-Serine Chemical Structure
  40. GC52384 NFAT Inhibitor (cell-permeable) (trifluoroacetate salt)

    Nuclear Factor Activated T cells Inhibitor, RRRRRRRRRRRGGGMAGPHPVIVITGPHEE, 11R-VIVIT

     A cell-permeable form of NFAT inhibitor NFAT Inhibitor (cell-permeable) (trifluoroacetate salt) Chemical Structure
  41. GC44518 Osteocalcin (1-49) (human) (trifluoroacetate salt) Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Osteocalcin (1-49) (human) (trifluoroacetate salt) Chemical Structure
  42. GC49061 Pam2CSK4 (trifluoroacetate salt)

    Pam2Cys-Ser-(Lys)4

     A bacterial lipopeptide and TLR2 agonist Pam2CSK4 (trifluoroacetate salt) Chemical Structure
  43. GC44567 Parathyroid Hormone (1-34) (human) (trifluoroacetate salt)

    LY333334, PTH (1-34)

     Parathyroid hormone (PTH) (1-34) is an N-terminal fragment of PTH that regulates bone remodeling. Parathyroid Hormone (1-34) (human) (trifluoroacetate salt) Chemical Structure
  44. GC45777 Peonidin 3-O-glucoside (chloride)

    Peonidin 3-β-D-glucopyranoside

     안토시아닌인 Peonidin 3-O-glucoside(chloride)는 인슐린 분비 촉진제 역할을 합니다. Peonidin 3-O-glucoside (chloride) Chemical Structure
  45. GC49148 Plitidepsin

    Aplidin, Dehydrodidemnin B

     플리티뎁신(아플리딘)은 eEF1A2(KD=80nM)를 표적으로 하는 강력한 항암제입니다. Plitidepsin Chemical Structure
  46. GC48023 Raloxifene-d4 (hydrochloride) Raloxifene-d4(염산염)는 Raloxifene으로 표시된 중수소입니다. Raloxifene(Keoxifene)은 benzothiophene 유래 선택적 에스트로겐 수용체 조절제(SERM)입니다. Raloxifene은 뼈와 지질에 대한 에스트로겐 길항작용과 유방과 자궁에 대한 길항작용이 있습니다. 랄록시펜은 유방암 및 골다공증 연구에 사용됩니다. Raloxifene-d4 (hydrochloride) Chemical Structure
  47. GC91920 Rhein-13C6

    Rheic Acid-13C6

     Rhein-13C6 GC 또는 LC-MS 정량 대황산의 내표로 사용하도록 설계되었습니다. Rhein-13C6 Chemical Structure
  48. GC44845 Rivenprost

    ONO-4819

    Prostaglandin E2 activates four distinct G protein-coupled receptors, EP1-4.

     Rivenprost Chemical Structure
  49. GC91690 TASP0277308 TASP0277308 is a sphingosine-1-phosphate receptor 1 (S1P1) antagonist (IC50 = 4.2 nM). TASP0277308 Chemical Structure
  50. GC45062 TNF-α Antagonist

    WP9QY

     TNF-α antagonist is an exocyclic peptide that mimics the critical TNF-α recognition loop on TNF receptor I complex and, thus, prevents ligand interaction with the receptor. TNF-α Antagonist Chemical Structure
  51. GC91977 TrkB Agonist Prodrug R13

    TrkB-IN-1; Tropomyosin-related Kinase B Agonist Prodrug R13; Tropomyosin-related Kinase B Inhibitor 1

     TrkB Agonist Prodrug R13 (R13) 는 원근구단백질 관련 효소 B (TrkB) 활성제 7,8 - 디옥시플라본의 전약 형태이다. TrkB Agonist Prodrug R13 Chemical Structure
  52. GC40233 Vitamin D3-d7 Vitamin D3-d7 is intended for use as an internal standard for the quantification of vitamin D3 by GC- or LC-MS. Vitamin D3-d7 Chemical Structure
  53. GC46235 Vitamin K1-d7

    α-Phylloquinone-d7, trans-Phylloquinone-d7

     An internal standard for the quantification of vitamin K1 Vitamin K1-d7 Chemical Structure
  54. GC17258 β-Estradiol-d3 β-Estradiol-d3는 내인성 에스트로겐 17β-Estradiol의 중수소 표기 화합물이다. β-Estradiol-d3 Chemical Structure

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