>>Signaling Pathways>> Membrane Transporter/Ion Channel>> Potassium Channel>>Ropivacaine mesylate

Ropivacaine mesylate

Catalog No.GC39843

로피바카인 메실레이트는 지속형 아미드 국소마취제로 척추차단술로 신경병성 통증을 효과적으로 차단한다.

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Ropivacaine mesylate Chemical Structure

Cas No.: 854056-07-8

Size 가격 재고 수량
10mM (in 1mL Water)
US$39.00
재고 있음
10mg
US$32.00
재고 있음
50mg
US$57.00
재고 있음

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Ropivacaine mesylate is an aminoamide compound, effectively blocks neuropathic pain. Ropivacaine mesylate is an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine mesylate inhibits pressure-induces lung endothelial hyperpermeability in models of acute hypertension[1][2].

[1]. Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321. [2]. Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28.

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