Ropivacaine mesylate |
| カタログ番号GC39843 |
メシル酸ロピバカインは、脊椎ブロック用の長時間作用型アミド局所麻酔薬であり、神経因性疼痛を効果的にブロックします。
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 854056-07-8
Sample solution is provided at 25 µL, 10mM.
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Ropivacaine mesylate is an aminoamide compound, effectively blocks neuropathic pain. Ropivacaine mesylate is an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine mesylate inhibits pressure-induces lung endothelial hyperpermeability in models of acute hypertension[1][2].
[1]. Li TF, et al. Epidural sustained release ropivacaine prolongs anti-allodynia and anti-hyperalgesia in developing and established neuropathic pain. PLoS One. 2015 Jan 24;10(1):e0117321. [2]. Milan Patel, et al. Ropivacaine Inhibits Pressure-Induced Lung Endothelial Hyperpermeability in Models of Acute Hypertension. Life Sci. 2019 Apr 1;222:22-28.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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