Scoulerine (Synonyms: (–)-Scoulerine, l-Scoulerine, (S)-Scoulerine) |
| Catalog No.GC39798 |
isoquinoline 알칼로이드인 Scoulerine((-)-Scoulerine)은 강력한 항유사분열 화합물입니다. Scoulerine은 또한 BACE1(β-부위 아밀로이드 전구체 단백질 절단 효소 1)의 억제제입니다. Scoulerine은 증식을 억제하고 세포주기를 정지시키며 암세포에서 세포자멸사를 유도합니다.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 6451-73-6
Sample solution is provided at 25 µL, 10mM.
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Scoulerine ((-)-Scoulerine), an isoquinoline alkaloid, is a potent antimitotic compound. Scoulerine is also an inhibitor of BACE1 (ß-site amyloid precursor protein cleaving enzyme 1). Scoulerine inhibits proliferation, arrests cell cycle, and induces apoptosis in cancer cells[1].
[1]. Habartova K, et al. Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells. Sci Rep. 2018;8(1):4829. Published 2018 Mar 19.
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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