SLP7111228 (hydrochloride) |
| Catalog No.GC44902 |
SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1449768-48-2
Sample solution is provided at 25 µL, 10mM.
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SLP7111228 is a potent and selective inhibitor of sphingosine kinase (SPHK) 1 with Ki values of 0.048 and >10 μM for SPHK1 and 2, respectively. It induces a concentration-dependent decrease in sphingosine-1-phosphate in U937 cells but has no effect on sphingosine levels. In vivo, SLP7111228 decreases blood levels of S1P in a dose-dependent manner in rats.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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