SYM 2081 |
| Catalog No.GC16101 |
SYM 2081은 고친화성 리간드이자 카이네이트 수용체의 강력하고 선택적인 작용제로서 [3H]-카이네이트 결합을 35nM의 IC50으로 억제하며, 이는 각각 AMPA 및 NMDA 수용체에 비해 카이네이트 수용체에 대해 거의 3000배 및 200배 선택성입니다[1 ].
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 31137-74-3
Sample solution is provided at 25 µL, 10mM.
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SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively[1].
References:
[1]. Lee JY, et al. Furthering pharmacological and physiological assessment of the glutamatergic receptors at the Drosophila neuromuscular junction. Comp Biochem Physiol C Toxicol Pharmacol. 2009 Nov;150(4):546-57.
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