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DNA Damage/DNA Repair

Research Areas

Products Related to DNA Damage/DNA Repair(1968)

  • GC74226 structure
    GC74226Biotin-PEG3-benzophenone
    CAS: 756525-96-9
    Purity: >99.00%

    Biotin-PEG3-benzophenone es benzofenona con etiqueta de biotina.

  • GC74250 structure
    GC74250Thymidine-13C10,15N2
    CAS: 1821188-00-4
    Purity: >99.00%

    Thymidine-13C10,15N2 es la 13C y 15N etiquetados Tmidine.

  • GC74261 structure
    GC74261(R)-(+)-O-Demethylbuchenavianine
    CAS: 1364123-68-1
    Purity: >98.00%

    (R)-(+)-O-Demethylbuchenavianine es un inhibide las cinasas dependientes de ciclina CDK.

  • GC74262 structure
    GC74262(S)-(-)-O-Demethylbuchenavianine
    CAS: 91147-18-1

    (S)-(-)-O-Demethylbuchenavianine (compuesto (S)-(−)-1) es un alcaloides flavonoides.

  • GC74316 structure
    GC74316ATR kinase substrate peptide
    Purity: >99.00%

    ATR kinase substrate peptide (compuesto 45) es un potente y selectivo inhibidor de ATR (Ataxia Telangiectasia y Rad3 relacionados) proteína quinasa (Ki=6 nM).

  • GC74324 structure
    GC74324Cdk5i peptide
    CAS: 2298317-00-5
    Purity: >99.00%

    Cdk5i peptide es un fragmento de péptido de 12 aminoácidos derivado de Cdk5.

  • GC74652 structure
    GC74652Exatecan Intermediate 2 hydrochloride
    CAS: 2437603-23-9
    Purity: >99.00%

    Exatecan Intermediate 2 hydrochloride (compuesto B) es un intermediario del exatecano (DX-8951,).

  • GC74653 structure
    GC74653Exatecan Intermediate 4
    CAS: 2436720-50-0

    Exatecan Intermediate 4 (compuesto B) es un intermediario del exatecano (DX-8951,).

  • GC74654 structure
    GC74654Exatecan Intermediate 4 dihydrochloride
    Purity: >99.00%

    Exatecan Intermediate 4 dihydrochloride es un intermedio de Exatecan (DX-8951,).

  • GC74656 structure
    GC74656Topoisomerase IIα-IN-8
    CAS: 1251578-67-2

    Topoisomerase IIα-IN-8 (compuesto 15) es un inhibidor débil de la topoisomerasa IIa (htIIa) del ADN humano, con una IC50 de 462 ± 38.0 ± M.

  • GC74684 structure
    GC74684Topoisomerase II inhibitor 14
    CAS: 305343-00-4
    Purity: >99.00%

    Topoisomerase II inhibitor 14 (compuesto 2f) es un potente inhibidor de la topoisomerasa II, con actividad anticancerosa.

  • GC74712 structure
    GC74712N-6-Methyl-2-deoxyadenosine-d3
    CAS: 1354782-02-7
    Purity: >99.00%

    N-6-Methyl-2-deoxyadenosine-d3 es el deuterio marcado n-6-metl-2-deoxiadenosina.

  • GC74727 structure
    GC74727JSH-009
    CAS: 2247481-08-7

    JSH-009 es un nuevo y altamente selectivo inhibide CDK9 crítico para regular el alargde la transcripción.

  • GC74733 structure
    GC74733Methoxyamine-d3 Hydrochloride
    CAS: 110220-55-8
    Purity: >99.00%

    Methoxyamine-d3 Hydrochloride (o-metldroxilamina D3) es el deuterio marcado como droclorde metoxiamina.

  • GC75685 structure
    GC75685PolQi1
    CAS: 2607139-80-8
    Purity: >98.00%

    PolQi1 is a selective inhibitor targeting the structure domain of DNA polymerase Polθ.

  • GC75826 structure
    GC75826YL-5092
    CAS: 3056857-07-6
    Purity: >98.00%

    YL-5092 is a novel, highly selective inhibitor of YTHDC1 (IC 50 =7.4nM; K D =29.6nM).

  • GC78755 structure
    GC78755ZW-251
    Purity: >98%

    ZW-251 is a glypican-3 ( GPC3 )-targeted antibody-drug conjugate ( ADC ) with topoisomerase-I inhibitory activity.

  • GC78756 structure
    GC78756Mocertatug rezetecan (DAR4)
    CAS: 3042848-25-6
    Purity: >98.00%

    Mocertatug rezetecan (DAR4) (HS-20089 (DAR4); GSK5733584 (DAR4)) is an antibody-drug conjugate ( ADC ) targeting B7-H4, composed of Mocertatug and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan.

  • GC78757 structure
    GC78757Mocertatug rezetecan (DAR6)
    CAS: 3042848-25-6
    Purity: >98.00%

    Mocertatug rezetecan (DAR6) (HS-20089 (DAR6); GSK5733584 (DAR6)) is an antibody-drug conjugate ( ADC ) targeting B7-H4, composed of Mocertatug and MC-Gly-Gly-Phe-Gly-(R)-Cyclopropane-Exatecan.

  • GC78759 structure
    GC787592-MSP-5-HA-VA-PAB-Exatecan
    CAS: 2878440-72-1
    Purity: >97.50%

    2-MSP-5-HA-Val-Cit-PAB-Exatecan (A-24) is a drug-linker conjugate for ADC.

  • GC78760 structure
    GC787602-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan
    CAS: 3115661-30-5
    Purity: >97.50%

    2-MSP(4-OMe)-5-HA-PEG8-VA-Exatecan is a Drug-linker conjugates for ADC consisting of the ADC Cytotoxin Exatecan and a linker.

  • GC78761 structure
    GC78761BLD1102
    CAS: 3025473-38-2
    Purity: >99.50%

    BLD1102 is a linker-load conjugate ( Drug-Linker Conjugates for ADC ) consisting of a DNA topoisomerase I inhibitor BCPT02 and a protease-cleavable linker.

  • GC78766 structure
    GC78766N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan)
    Purity: >98.00%

    N-(Mal)-N-(PEG8-Val-Cit-PAB-MMAE)-N-(PEG8-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan, and an ADC linker composition.

  • GC78767 structure
    GC78767N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan)
    Purity: >98.00%

    N-(DBCO-PEG4)-N-(PEG4-Val-Cit-PAB-MMAE)-N-(PEG4-Val-Cit-PAB-Exatecan) is a drug-linker conjugate for ADC (Drug-Linker Conjugate for ADC), consisting of a tubulin polymerization inhibitor MMAE and a DNA topoisomerase I inhibitor Exatecan, and an ADC linker composition.