1-Arachidonoyl Glycerol (Synonyms: 1AG) |
| Katalog-Nr.GC40469 |
The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 35474-99-8
Sample solution is provided at 25 µL, 10mM.
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The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands. 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand. However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.
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