1-Oleoyl-2-acetyl-sn-glycerol (Synonyms: OAG) |
| Katalog-Nr.GC42012 |
1-Oleoyl-2-acetyl-sn-Glycerol ist ein synthetisches, zellgÄngiges Diacylglycerol-Analogon.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 86390-77-4
Sample solution is provided at 25 µL, 10mM.
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OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.[1]
Reference:
[1]. Nishizuka, Y. The role of protein kinase C in cell surface signal transduction and tumour promotion. Nature 308, 693-697 (1984).
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