Sinefungin |
| Katalog-Nr.GC34784 |
Sinefungin ist ein potenter Inhibitor der Virion-mRNA(Guanin-7-)-Methyltransferase, mRNA(Nukleosid-2'-)-Methyltransferase und der Virusvermehrung.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 58944-73-3
Sample solution is provided at 25 µL, 10mM.
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Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication[1]. Sinefungin, a SET7/9 inhibitor, ameliorates renal fibrosis by inhibiting H3K4 methylation [2].
[1]. Pugh CS, et al. Sinefungin, a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. J Biol Chem. 1978 Jun 25;253(12):4075-7. [2]. Sasaki K, et al. Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis. J Am Soc Nephrol. 2016 Jan;27(1):203-15.
Average Rating: 5 (Based on Reviews and 24 reference(s) in Google Scholar.)
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